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Article

An integrated meta-analysis of two variants in HOXA1/HOXB1 and their effect on the risk of autism spectrum disorders.

PloS one - 1 Jan 2011

Song Ran-Ran, Zou Li, Zhong Rong, Zheng Xia-Wen, Zhu Bei-Bei, Chen Wei, Liu Li, Miao Xiao-Ping

Abstract excerpt

BACKGROUND: HOXA1 and HOXB1 have been strongly posed as candidate genes for autism spectrum disorders (ASD) given their important role in the development of hindbrain. The A218G (rs10951154) in HOXA1 and the insertion variant in HOXB1 (nINS/INS, rs72338773) were of special interest for ASD but with inconclusive results. Thus, we conducted a meta-analysis integrating case-control and transmission/disequilibrium...

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Identifiers

PMID: 21980499
DOI: 10.1371/journal.pone.0025603
PMCID: PMC3183057

Genes

INS
HOXA1
HOXB1

Provenance

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