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Article

A differential network approach to exploring differences between biological states: an application to prediabetes.

PloS one - 1 Jan 2011

Valcárcel Beatriz, Würtz Peter, Seich al Basatena Nafisa-Katrin, Tukiainen Taru, Kangas Antti J, Soininen Pasi, Järvelin Marjo-Riitta, Ala-Korpela Mika, Ebbels Timothy M, de Iorio Maria

Abstract excerpt

BACKGROUND: Variations in the pattern of molecular associations are observed during disease development. The comprehensive analysis of molecular association patterns and their changes in relation to different physiological conditions can yield insight into the biological basis of disease-specific phenotype variation. METHODOLOGY: Here, we introduce a formal statistical method for the differential analysis of...

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PMID: 21980352
DOI: 10.1371/journal.pone.0024702
PMCID: PMC3181317

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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