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Article

PAX8 mutation disturbing thyroid follicular growth: a case report.

The Journal of clinical endocrinology and metabolism - 1 Dec 2011

Narumi Satoshi, Yoshida Akira, Muroya Koji, Asakura Yumi, Adachi Masanori, Fukuzawa Ryuji, Kameyama Kaori, Hasegawa Tomonobu

Abstract excerpt

CONTEXT: Heterozygous inactivating PAX8 mutations cause congenital hypothyroidism. Although more than 30 mutation carriers have been reported, no histological examination of the thyroid has been conducted. OBJECTIVE: The objective of this study was to document the histological characteristics of the thyroid tissue harboring a PAX8 mutation. SUBJECTS AND METHODS: The patient was a 40-yr-old female, whose two...

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Source

Identifiers

PMID: 21976720
DOI: 10.1210/jc.2011-1114

Genes

PAX8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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