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Article

Sequence diversity within the capsular genes of Streptococcus pneumoniae serogroup 6 and 19.

PloS one - 1 Jan 2011

Elberse Karin, Witteveen Sandra, van der Heide Han, van de Pol Ingrid, Schot Corrie, van der Ende Arie, Berbers Guy, Schouls Leo

Abstract excerpt

The main virulence factor of Streptococcus pneumoniae is the capsule. The polysaccharides comprising this capsule are encoded by approximately 15 genes and differences in these genes result in different serotypes. The aim of this study was to investigate the sequence diversity of the capsular genes of serotypes 6A, 6B, 6C, 19A and 19F and to explore a possible effect of vaccination on variation and distribution...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21949837
DOI: 10.1371/journal.pone.0025018
PMCID: PMC3174988

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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