Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Connexin channels in congenital skin disorders.

Seminars in cell & developmental biology - 1 Feb 2016

Lilly Evelyn, Sellitto Caterina, Milstone Leonard M, White Thomas W

Abstract excerpt

Gap junctions and hemichannels comprised of connexins influence epidermal proliferation and differentiation. Significant advances in our understanding of the functional role of connexins in the skin have been made by studying the diseases caused by connexin mutations. Eleven clinically defined cutaneous disorders with an overlapping spectrum of phenotypes are caused by mutations in five different connexin genes,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Connexins
Share to Epidermis
Share to Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Skin Diseases

Source

Open in PubMed Open full text

Identifiers

PMID: 26775130
DOI: 10.1016/j.semcdb.2015.11.018
PMCID: PMC4779425

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Connexin channels in congenital skin disorders.PMID 26775130Read ↗

Connexin 43 Mutations Lead to Increased Hemichannel Functionality in Skin Disease.Semantic proximity Read ↗

Connexins: a connection with the skin.Semantic proximity Read ↗

Connexin mutations in hearing loss, dermatological and neurological disorders.Semantic proximity Read ↗

Gap junctions: basic structure and function.Semantic proximity Read ↗

Gap junction diseases of the skin.Semantic proximity Read ↗

Overview of skin diseases linked to connexin gene mutations.Semantic proximity Read ↗

The role of connexins in ear and skin physiology - functional insights from disease-associated mutations.Semantic proximity Read ↗

Key functions for gap junctions in skin and hearing.Semantic proximity Read ↗

Connexin-26 mutations in deafness and skin disease.Semantic proximity Read ↗

Connexin mutations causing skin disease and deafness increase hemichannel activity and cell death when expressed in Xenopus oocytes.Semantic proximity Read ↗

Connexin26 Mutations Causing Palmoplantar Keratoderma and Deafness Interact with Connexin43, Modifying Gap Junction and Hemichannel Properties.Semantic proximity Read ↗

Connexin mutations in skin disease and hearing loss.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.