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Article

Progress in recombinant DNA-derived vaccines for Lassa virus and filoviruses.

Virus research - 1 Dec 2011

Grant-Klein Rebecca J, Altamura Louis A, Schmaljohn Connie S

Abstract excerpt

Developing vaccines for highly pathogenic viruses such as those causing Lassa, Ebola, and Marburg hemorrhagic fevers is a daunting task due to both scientific and logistical constraints. Scientific hurdles to overcome include poorly defined relationships between pathogenicity and protective immune responses, genetic diversity of viruses, and safety in a target population that includes a large number of...

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Identifiers

PMID: 21925552
DOI: 10.1016/j.virusres.2011.09.005

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