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Article

An Overview of Live Attenuated Recombinant Pseudorabies Viruses for Use as Novel Vaccines

1 Jan 2014

Abstract excerpt

Pseudorabies virus (PRV) is a double-stranded, DNA-based swine virus with a genome approximating 150 kb in size. PRV has many nonessential genes which can be replaced with genes encoding heterologous antigens but without deleterious effects on virus propagation. Recombinant PRVs expressing both native and foreign antigens are able to stimulate immune responses. In this paper, we review the current status of live...

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Identifiers

PMID: 24995348
DOI: 10.1155/2014/824630

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