Article
Characterisation of sequences required for RNA initiation from the PGK promoter of Saccharomyces cerevisiae.
Nucleic acids research - 11 Jun 1990
Rathjen J, Mellor J
Abstract excerpt
In the phosphoglycerate kinase (PGK) gene of yeast, as in other highly expressed yeast genes, the sequences surrounding the site of RNA initiation have a loosely conserved structure of a CT rich stretch followed by the tetranucleotide CAAG. Using internal deletions and insertions we have identified the elements in the PGK promoter which are required for correct RNA initiation at the CAAG sequence at -39. The...
Topics
- Base Sequence
- Molecular Sequence Data
- Mutation
- Phosphoglycerate Kinase
- Promoter Regions, Genetic
- RNA, Fungal
- RNA, Messenger
- Saccharomyces cerevisiae
- Sequence Homology, Nucleic Acid
- Transcription, Genetic