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Article

Genomic instability in breast and ovarian cancers: translation into clinical predictive biomarkers.

Cellular and molecular life sciences : CMLS - 1 Jan 2012

Vollebergh Marieke A, Jonkers Jos, Linn Sabine C

Abstract excerpt

Breast and ovarian cancer are among the most common malignancies diagnosed in women worldwide. Together, they account for the majority of cancer-related deaths in women. These cancer types share a number of features, including their association with hereditary cancer syndromes caused by heterozygous germline mutations in BRCA1 or BRCA2. BRCA-associated breast and ovarian cancers are hallmarked by genomic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21922196
DOI: 10.1007/s00018-011-0809-0
PMCID: PMC11114988

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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