Article
Resistance to thyroid hormone accompanied by Graves' disease.
Internal medicine (Tokyo, Japan) - 1 Jan 2011
Shiwa Tsuguka, Oki Kenji, Awaya Tomokazu, Nakanishi Shuhei, Yamane Kiminori
Abstract excerpt
Resistance to thyroid hormone (RTH) is characterized by elevated serum levels of thyroid hormones and normal or slightly increased serum thyrotropin (TSH) levels. Recently it has been suggested that chronic TSH stimulation in RTH activates intrathyroidal lymphocytes, leading to thyroid damage and autoimmune thyroid disease (AITD). Therefore, individuals with RTH have an increased likelihood of AITD compared to...
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