Article
Polymorphism analysis of MTHFR, factor II, and factor V genes in the Pomeranian population of Espirito Santo, Brazil.
Genetic testing and molecular biomarkers - 1 Mar 2012
Stur Elaine, Silveira Amanda Nunes, Selvatici Livia Serra, Alves Lyvia Neves Rebello, de Vargas Wolfgramm Eldamária, Tovar Thaís Tristão, De Nadai Sartori Mariana Penha, de Paula Flavia, Louro Iuri Drumond
Abstract excerpt
Pomeranian populations worldwide immigrated originally from the north of Europe, and because of their preferential marriage, religion, and cultural habits, they show little or no reproductive mixing with local populations. Methylenetetrahydrofolate reductase gene (MTHFR) C677T, Factor V Leiden, and Factor II G20210A polymorphisms are linked to augmented clotting and their frequencies may vary according to...
Topics
- Alleles
- Brazil
- Factor V
- Gene Flow
- Gene Frequency
- Genetics, Population
- Humans
- Methylenetetrahydrofolate Reductase (NADPH2)
- Polymerase Chain Reaction
- Polymorphism, Genetic