Article
[Hormone receptors and HER-2 changes during breast cancer progression: clinical implications].
Bulletin du cancer - 1 Oct 2011
Jacot William, Pouderoux Stéphane, Bibeau Frédéric, Leaha Cristina, Chateau Marie-Christine, Chapelle Angélique, Romieu Gilles
Abstract excerpt
Breast cancer remains a major public health problem. Even if there is an increase in this cancer curability, metastatic breast cancer remains a lethal disease in the vast majority of cases. Therapeutic advances in the chemotherapeutic and targeted therapies fields induced an increase in survival, however the proportion of long survivors remains low. Phenotypic instability, an early process initiated during tumour...
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