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Article

Analysis of 4 single-nucleotide polymorphisms in relation to cervical dysplasia and cancer development using a high-throughput ligation-detection reaction procedure.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society - 1 Dec 2011

von Keyserling Helmut, Bergmann Thomas, Schuetz Miriam, Schiller Ursula, Stanke Jonas, Hoffmann Corinna, Schneider Achim, Lehrach Hans, Dahl Andreas, Kaufmann Andreas M

Abstract excerpt

BACKGROUND: Host genetic characteristics and environmental factors may correlate with risk for cervical cancer development. Here we describe a retrospective screening study for single nucleotide polymorphisms (SNPs) in genetic markers TP53, MTHFR, CYP1A1, and CYP2E1 in 749 patients. METHODS: A multiplex ligation-dependent polymerase chain reaction approach was applied. We used archived material from human...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21897271
DOI: 10.1097/IGC.0b013e31822b6299

Genes

MTHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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