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Article

Altered patterns of brain activity during transient sadness in children at familial risk for major depression.

Journal of affective disorders - 1 Dec 2011

Lévesque Mélissa L, Beauregard Mario, Ottenhof Koen W, Fortier Emilie, Tremblay Richard E, Brendgen Mara, Pérusse Daniel, Dionne Ginette, Robaey Philippe, Vitaro Frank, Boivin Michel, Booij Linda

Abstract excerpt

INTRODUCTION: We used functional magnetic resonance imaging (fMRI) to investigate the neural correlates of sadness, the prevailing mood in major depression (MD), in a prospective, well-documented community sample followed since birth. METHODS: The children, comprising 136 children (65 boys and 71 girls) of mothers with varying levels of depressive symptomatology, were scanned - using a 1.5-Tesla system - while...

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Identifiers

PMID: 21890212
DOI: 10.1016/j.jad.2011.08.010

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