Article
Co-existence of major and minor viral populations from two different origins in patients secondarily infected with dengue virus serotype 2 in Bangkok.
Biochemical and biophysical research communications - 16 Sept 2011
Puiprom Orapim, Yamashita Akifumi, Sasayama Mikiko, Limkittikul Kriengsak, Boonha Khwanchit, Jittmitraphap Akanitt, Leaungwutiwong Pornsawan, Kurosu Takeshi, Ramasoota Pongrama, Ikuta Kazuyoshi
Abstract excerpt
Generally, RNA viruses exhibit significant genetic diversity that sometimes effect viral fitness in infected hosts and probably also pathogenesis. Dengue viruses (DENVs) consist of four antigenically distinct serotypes. All the serotypes of DENV can cause mild to severe dengue illnesses. In this study, we examined the sequence variation of DENV in plasma obtained from four patients living in Bangkok who had been...
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