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Article

Rapid whole genome optical mapping of Plasmodium falciparum.

Malaria journal - 26 Aug 2011

Riley Matthew C, Kirkup Benjamin C, Johnson Jake D, Lesho Emil P, Ockenhouse Christian F

Abstract excerpt

BACKGROUND: Immune evasion and drug resistance in malaria have been linked to chromosomal recombination and gene copy number variation (CNV). These events are ideally studied using comparative genomic analyses; however in malaria these analyses are not as common or thorough as in other infectious diseases, partly due to the difficulty in sequencing and assembling complete genome drafts. Recently, whole genome...

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Identifiers

PMID: 21871093
DOI: 10.1186/1475-2875-10-252
PMCID: PMC3173401

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