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Article

Cohen syndrome-associated protein, COH1, is a novel, giant Golgi matrix protein required for Golgi integrity.

The Journal of biological chemistry - 28 Oct 2011

Seifert Wenke, Kühnisch Jirko, Maritzen Tanja, Horn Denise, Haucke Volker, Hennies Hans Christian

Abstract excerpt

Loss-of-function mutations in the gene COH1, also known as VPS13B, lead to autosomal recessive Cohen syndrome. However, the cellular distribution and function of the encoded protein COH1 (3997 amino acids), which lacks functional homologies to other mammalian proteins, have remained enigmatic. We...

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Identifiers

PMID: 21865173
DOI: 10.1074/jbc.M111.267971
PMCID: PMC3199510

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21865173-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Cohen syndrome-associated protein, COH1, is a novel, giant Golgi matrix protein required for Golgi integrity.PMID 21865173Read ↗

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