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Article

Phylodynamics and molecular evolution of influenza A virus nucleoprotein genes in Taiwan between 1979 and 2009.

PloS one - 1 Jan 2011

Lin Jih-Hui, Chiu Shu-Chun, Cheng Ju-Chien, Chang Hui-Wen, Hsiao Kuang-Liang, Lin Yung-Cheng, Wu Ho-Sheng, Salemi Marco, Liu Hsin-Fu

Abstract excerpt

BACKGROUND: Many studies concentrate on variation in the hemagglutinin glycoprotein (HA) because of its significance in host immune response, the evolution of this virus is even more complex when other genome segments are considered. Recently, it was found that cytotoxic T lymphocytes (CTL) play an important role in immunity against influenza and most CTL epitopes of human influenza viruses were remarkably...

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PMID: 21858124
DOI: 10.1371/journal.pone.0023454
PMCID: PMC3155553

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