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Myocilin gene implicated in primary congenital glaucoma

8 Feb 2005

Abstract excerpt

Primary congenital glaucoma (PCG) has been associated with CYP1B1 gene (2p21), with a predominantly autosomal recessive mode of inheritance. Our earlier studies attributed CYP1B1 mutations to only 40% of Indian PCG cases. In this study, we included 72 such PCG cases where CYP1B1 mutations were detected in only 12 patients in heterozygous condition, implying involvement of other gene(s). On screening these...

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PMID: 15733270
DOI: 10.1111/j.1399-0004.2005.00411.x

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