Article
Inference of population mutation rate and detection of segregating sites from next-generation sequence data.
Genetics - 1 Oct 2011
Kang Chul Joo, Marjoram Paul
Abstract excerpt
We live in an age in which our ability to collect large amounts of genome-wide genetic variation data offers the promise of providing the key to the understanding and treatment of genetic diseases. Over the next few years this effort will be spearheaded by so-called next-generation sequencing technologies, which provide vast amounts of short-read sequence data at relatively low cost. This technology is often used...
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