Article
Identification of SPOCK2 as a susceptibility gene for bronchopulmonary dysplasia.
American journal of respiratory and critical care medicine - 15 Nov 2011
Hadchouel Alice, Durrmeyer Xavier, Bouzigon Emmanuelle, Incitti Roberto, Huusko Johanna, Jarreau Pierre-Henri, Lenclen Richard, Demenais Florence, Franco-Montoya Marie-Laure, Layouni Inès, Patkai Juliana, Bourbon Jacques, Hallman Mikko, Danan Claude, Delacourt Christophe
Abstract excerpt
RATIONALE: Bronchopulmonary dysplasia is the most common chronic respiratory disease in premature infants. Genetic factors might contribute to bronchopulmonary dysplasia susceptibility. OBJECTIVES: To identify genetic variants involved in bronchopulmonary dysplasia through a genome-wide association study. METHODS: We prospectively evaluated 418 premature neonates (gestational age <28 wk), of whom 22% developed...
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