Article
Maintained sensitivity to EGFR tyrosine kinase inhibitors in EGFR-mutant lung cancer recurring after adjuvant erlotinib or gefitinib.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Oct 2011
Oxnard Geoffrey R, Janjigian Yelena Y, Arcila Maria E, Sima Camelia S, Kass Samantha L, Riely Gregory J, Pao William, Kris Mark G, Ladanyi Marc, Azzoli Christopher G, Miller Vincent A
Abstract excerpt
PURPOSE: Given the unprecedented efficacy of EGFR tyrosine kinase inhibitors (TKI) in advanced EGFR-mutant lung cancer, adjuvant TKI therapy is an appealing strategy. However, there are conflicting findings regarding the potential benefit of adjuvant EGFR-TKI in patients with lung cancer harborin...
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