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Article

Stage-specific malformations and phenotypic changes induced in embryos of amphibian (Xenopus tropicalis) by triphenyltin.

Ecotoxicology and environmental safety - 1 Oct 2011

Yuan Jing, Zhang Xiaoli, Yu Lin, Sun Zhi, Zhu Pan, Wang Xinhong, Shi Huahong

Abstract excerpt

Tributyltin (TBT) and triphenyltin (TPT) can induce unique malformations in embryos of amphibian (Xenopus tropicalis). We further exposed X. tropicalis embryos to TPT during different stages. Severe malformations were observed in the embryos after exposure to 5-10 μg Sn/L TPT during S32-40 and S40-46. Comparatively, the embryos showed slight or moderate malformations after exposure during S10-25, S25-32 or...

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PMID: 21831434
DOI: 10.1016/j.ecoenv.2011.07.020

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