Article
Effect-directed analysis of municipal landfill soil reveals novel developmental toxicants in the zebrafish Danio rerio.
Environmental science & technology - 1 Oct 2011
Legler Juliette, van Velzen Martin, Cenijn Peter H, Houtman Corine J, Lamoree Marja H, Wegener Jan Willem
Abstract excerpt
Effect-directed analysis (EDA) is an approach used to identify (unknown) contaminants in complex samples which cause toxicity, using a combination of biology and chemistry. The goal of this work was to apply EDA to identify developmental toxicants in soil samples collected from a former municipal landfill site. Soil samples were extracted, fractionated, and tested for developmental effects with an embryotoxicity...
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