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Article

MDM2 regulates MYCN mRNA stabilization and translation in human neuroblastoma cells

8 Aug 2011

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 21822304
DOI: 10.1038/onc.2011.343

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Related research

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Research trail→

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MDM2 regulates MYCN mRNA stabilization and translation in human neuroblastoma cellsPMID 21822304Read ↗

MYCN silencing induces differentiation and apoptosis in human neuroblastoma cellsSemantic proximity Read ↗

The long noncoding RNA lncNB1 promotes tumorigenesis by interacting with ribosomal protein RPL35Semantic proximity Read ↗

The p53 regulatory gene <i>MDM2</i> is a direct transcriptional target of MYCN in neuroblastomaSemantic proximity Read ↗

Mdm2 Deficiency Suppresses MYCN-Driven Neuroblastoma Tumorigenesis In VivoSemantic proximity Read ↗

The RNA‐helicase DDX21 upregulates CEP55 expression and promotes neuroblastomaSemantic proximity Read ↗

FOXR2 Stabilizes MYCN Protein and Identifies Non–MYCN-Amplified Neuroblastoma Patients With Unfavorable OutcomeSemantic proximity Read ↗

Next‐generation RNA sequencing reveals differential expression of MYCN target genes and suggests the mTOR pathway as a promising therapy target in <i>MYCN‐</i>amplified neuroblastomaSemantic proximity Read ↗

KAP1 stabilizes MYCN mRNA and promotes neuroblastoma tumorigenicity by protecting the RNA m6A reader YTHDC1 protein degradationSemantic proximity Read ↗

Crosstalk between MYCN and MDM2-p53 signal pathways regulates tumor cell growth and apoptosis in neuroblastomaSemantic proximity Read ↗

MYCN-mediated regulation of the MRP1 promoter in human neuroblastomaSemantic proximity Read ↗

Inhibitors of ribosome biogenesis repress the growth of MYCN-amplified neuroblastomaSemantic proximity Read ↗

HuD, a neuronal-specific RNA-binding protein, is a putative regulator of N-myc pre-mRNA processing/stability in malignant human neuroblastsSemantic proximity Read ↗

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