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Article

VEGF expression is related to good response and long progression-free survival in gastrointestinal stromal tumor patients treated with Sunitinib.

Diagnostic molecular pathology : the American journal of surgical pathology, part B - 1 Sept 2011

Koh Youngil, Lee Hee Eun, Im Seock-Ah, Kim Se-Hyung, Kim Tae Min, Han Sae-Won, Oh Do-Youn, Kim Jee Hyun, Lee Se-Hoon, Kim Dong-Wan, Kim Tae-You, Kim Woo-Ho, Heo Dae Seog, Bang Yung-Jue

Abstract excerpt

We intended to find predictive markers in advanced gastrointestinal stromal tumor patients treated with sunitinib. Korean patients who received sunitinib after imatinib failure for advanced gastrointestinal stromal tumor were studied. Genotyping for KIT and PDGFRA were performed. An immunohistochemical stain for PDGFR-α, PDGFR-β, and vascular endothelial growth factor (VEGF) was performed. A total of 22 patients...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21817899
DOI: 10.1097/PDM.0b013e3182107ea0

Genes

KIT
PDGFRA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

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VEGF expression is related to good response and long progression-free survival in gastrointestinal stromal tumor patients treated with Sunitinib.PMID 21817899Read ↗

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Secondary mutations of c-KIT contribute to acquired resistance to imatinib and decrease efficacy of sunitinib in Chinese patients with gastrointestinal stromal tumors.Semantic proximity Read ↗

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