Article
Antibiotics and the post-genome revolution.
Current opinion in microbiology - 1 Oct 2011
Amini Sasan, Tavazoie Saeed
Abstract excerpt
The emergence of pathogenic bacteria resistant to multiple antimicrobial agents is turning into a major crisis in human and veterinary medicine. This necessitates a serious re-evaluation of our approaches toward antibacterial drug discovery and use. Concurrent advances in genomics including whole-genome sequencing, genotyping, and gene expression profiling have the potential to transform our basic understanding...
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