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Article

The H6D variant of NAG-1/GDF15 inhibits prostate xenograft growth in vivo.

The Prostate - 1 May 2012

Wang Xingya, Chrysovergis Kali, Bienstock Rachelle J, Shim Minsub, Eling Thomas E

Abstract excerpt

BACKGROUND: Non-steroidal anti-inflammatory drug-activated gene (NAG-1), a divergent member of the transforming growth factor-beta superfamily, has been implicated in many cellular processes, including inflammation, early bone formation, apoptosis, and tumorigenesis. Recent clinical studies suggests that a C to G single nucleotide polymorphism at position 6 (histidine to aspartic acid substitution, or H6D) of the...

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Identifiers

PMID: 21809352
DOI: 10.1002/pros.21471
PMCID: PMC3209492

Genes

GDF15

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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The H6D variant of NAG-1/GDF15 inhibits prostate xenograft growth in vivo.PMID 21809352Read ↗

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NSAID Activated Gene (NAG-1), a Modulator of TumorigenesisSemantic proximity Read ↗

NAG-1/GDF15 Transgenic Mouse Has Less White Adipose Tissue and a Reduced Inflammatory ResponseSemantic proximity Read ↗

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