Article
Factor V Leiden and inflammatory bowel disease: a systematic review and meta-analysis.
Journal of gastroenterology - 1 Oct 2011
Liang Jie, Wu Shengjun, Feng Bin, Lei Shaoni, Luo Guanhong, Wang Jingbo, Li Kai, Li Xiaohua, Xie Huahong, Zhang Dexin, Wang Xin, Wu Kaichun, Miao Danmin, Fan Daiming
Abstract excerpt
BACKGROUND: Recent studies proved that inflammatory bowel disease (IBD) patients had a higher risk of thromboembolism and a Factor V Leiden mutation that prevents the efficient inactivation of factor V, which leads to thromboembolism and thus contributes to a high potential risk of IBD. However, the relationship between Factor V Leiden mutation and IBD remains controversial. METHODS: We conducted a systematic...
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