Article
Thrombophilia and inflammatory bowel disease: does factor V mutation have a role?
European journal of gastroenterology & hepatology - 1 Oct 1998
Over H H, Ulgen S, Tuğlular T, Tezel A, Avşar E, Geyik G, Başgül S, Sayhan N, Ulusoy N, Kalayci C, Tözün N
Abstract excerpt
BACKGROUND: An increased tendency for thromboembolism is a well known problem of inflammatory bowel disease (IBD). Microvascular thrombosis has also been claimed as a pathogenic factor in IBD. Recently a point mutation in the gene coding factor V (FV Leiden) has been identified in various thromboembolic diseases, but the role in IBD is unknown. OBJECTIVE: To determine the frequency of FV Leiden in IBD patients...
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