Article
The CRISPLD2 gene is involved in cleft lip and/or cleft palate in a Chinese population.
Birth defects research. Part A, Clinical and molecular teratology - 1 Oct 2011
Shen Xi, Liu Rui-Min, Yang Lan, Wu Hua, Li Pei-Qiang, Liang Ya-Ling, Xie Xiao-Dong, Yao Ting, Zhang Ting-Ting, Yu Min
Abstract excerpt
BACKGROUND: Nonsyndromic cleft lip and/or cleft palate (NSCLP) are common congenital anomalies in humans, the etiologies of which are complex and associated with both genetic and environmental factors. Previous data suggested single nucleotide polymorphisms (SNPs) of rs1546124, rs4783099, and rs16974880 of the CRISPLD2 gene were associated with an increased risk of NSCLP; however, subsequent studies have yielded...
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