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Article

[Analysis of the prevalence of CCR5 coreceptor antagonist resistance mutations among HIV-1 variants in Russia].

Voprosy virusologii - 1 Jan 2000

Vasil'ev A V, Kazennova E V, Bobkova M R

Abstract excerpt

The authors studied the prevalence of mutations associated with resistance to the CCRS coreceptor antagonists maraviroc and vicriviroc in Russia. Most (93.6%) patients infected with HIV-1 genetic subtype A (IDU-A), predominant in the CIS countries, were found to have maraviroc resistance mutations. These mutations appear to reflect the natural genome polymorphism characteristic of the variant IDU-A. Maraviroc...

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Identifiers

PMID: 21786625

Genes

CCR5

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