[Association of gene TP53 polymorphic marker Pro72Arg with clinical characteristics of chronic glomerulonephritis].

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Article

[Association of gene TP53 polymorphic marker Pro72Arg with clinical characteristics of chronic glomerulonephritis].

Terapevticheskii arkhiv - 1 Jan 2011

Kamyshova E S, Shvetsov M Iu, Shestakov A E, Kutyrina I M, Nosikov V V

Abstract excerpt

AIM: To study association of gene TP53 polymorphic marker Pro72Arg coding synthesis of p53 protein with onset, course and progress of chronic glomerulonephritis (CGN). MATERIAL AND METHODS: We examined 126 patients (63 males and 63 females, mean age 38.8 +/- 13.2 years) with CGN duration 13.0 +/- 9.1 years. When analyzing genetic predisposition to CGN, we compared incidence rate of alleles/genotypes of...

Topics

Adolescent
Adult
Aged
Alleles
Amino Acid Substitution
Arginine
Chronic Disease
Disease Progression
Female
Genetic Markers
Glomerulonephritis
Humans
Male
Middle Aged
Proline
Tumor Suppressor Protein p53
Young Adult

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Open in PubMed

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PMID: 21786572

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