Article
Renin-angiotensin system polymorphisms in relation to hypertension status and obesity in a Tunisian population.
Molecular biology reports - 1 Apr 2012
Mehri Sounira, Mahjoub Sinda, Hammami Sonia, Zaroui Amira, Frih Ameur, Betbout Fathi, Mechmeche Rachid, Hammami Mohamed
Abstract excerpt
Essential hypertension (HTA) is the clinical expression of a disordered interaction between the genetic, physiological, and biochemical systems that under usual conditions maintain cardiovascular homeostasis. We studied the effects of the angiotensinogen M235T, angiotensin converting enzyme insertion/deletion (ACE I/D), and angiotensin II receptor 1 (AT1R) A1166C gene polymorphisms on the risk of HTA and to...
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