Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A computational framework of host-based drug repositioning for broad-spectrum antivirals against RNA viruses

7 Feb 2021

Abstract excerpt

RNA viruses are responsible for many zoonotic diseases that post great challenges for public health. Effective therapeutics against these viral infections remain limited. Here, we deployed a computational framework for host-based drug repositioning to predict potential antiviral drugs from 2,352 approved drugs and 1,062 natural compounds embedded in herbs of traditional Chinese medicine. By systematically...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Computational Drug Discovery Methods
Share to interferon and immune responses
Share to Mosquito-borne diseases and control

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33665567
DOI: 10.1016/j.isci.2021.102148

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A computational framework of host-based drug repositioning for broad-spectrum antivirals against RNA virusesPMID 33665567Read ↗

A Computational Framework of Host-Based Drug Repositioning for Broad-Spectrum Antivirals against RNA VirusesSemantic proximity Read ↗

Network-Based Identification and Experimental Validation of Drug Candidates Toward SARS-CoV-2 via Targeting Virus–Host InteractomeSemantic proximity Read ↗

Ontological and Bioinformatic Analysis of Anti-Coronavirus Drugs and Their Implication for Drug Repurposing against COVID-19Semantic proximity Read ↗

Potentially repurposable drugs for COVID-19 identified from SARS-CoV-2 Host Protein InteractomeSemantic proximity Read ↗

Identification of Drugs Targeting Multiple Viral and Human Proteins Using Computational Analysis for Repurposing Against COVID-19Semantic proximity Read ↗

Drug repositioning for dengue haemorrhagic fever by integrating multiple omics analysesSemantic proximity Read ↗

Virus-host interaction networks as new antiviral drug targets for IAV and SARS-CoV-2Semantic proximity Read ↗

Genomics functional analysis and drug screening of SARS-CoV-2Semantic proximity Read ↗

Identification of drugs targeting multiple viral and human proteins using computational analysis for repurposing against COVID-19Semantic proximity Read ↗

Systematic Approaches towards the Development of Host-Directed Antiviral TherapeuticsSemantic proximity Read ↗

Genetic screens for the control of influenza virus replication: from meta-analysis to drug discoverySemantic proximity Read ↗

A data-driven drug repositioning framework discovered a potential therapeutic agent targeting COVID-19Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.