Article
Primer and interviews: promises and realities of induced pluripotent stem cells.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Aug 2011
Kiefer Julie C
Abstract excerpt
In 2006, Yamanaka's group announced they had discovered the proverbial "fountain of youth" for human cells, forever changing the field of stem cell research. After misexpressing within them a cocktail of four genes, adult somatic cells revert into an embryonic stem cell (ESC)-like state. These so-called induced pluripotent stem cells (iPSCs) can differentiate into a wide variety of cell types, seemingly bypassing...
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