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Research and therapy with induced pluripotent stem cells (iPSCs): social, legal, and ethical considerations

21 Nov 2019

Abstract excerpt

Induced pluripotent stem cells (iPSCs) can self-renew indefinitely in culture and differentiate into all specialized cell types including gametes. iPSCs do not exist naturally and are instead generated ("induced" or "reprogrammed") in culture from somatic cells through ectopic co-expression of defined pluripotency factors. Since they can be generated from any healthy person or patient, iPSCs are considered as a...

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PMID: 31753034
DOI: 10.1186/s13287-019-1455-y

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