Characterization of BK virus variants rescued from human tumours and tumour cell lines.

doi:10.1099/0022-1317-71-11-2731

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Article

Characterization of BK virus variants rescued from human tumours and tumour cell lines.

The Journal of general virology - 1 Nov 1990

Negrini M, Rimessi P, Mantovani C, Sabbioni S, Corallini A, Gerosa M A, Barbanti-Brodano G

Abstract excerpt

Episomal BK virus (BKV) DNA was detected in primary human brain tumours, in Kaposi's sarcoma and in cell lines from brain tumours. Ewing sarcoma and osteogenic sarcoma. Infectious BKV was rescued from several tumours and tumour cell lines by transfection of total cellular DNA into human embryonic fibroblasts. Restriction endonuclease and nucleotide sequence analysis showed that all the rescued viruses are similar...

Topics

Animals
BK Virus
Base Sequence
DNA, Viral
Enhancer Elements, Genetic
Genetic Variation
Glioma
Humans
Mice
Molecular Sequence Data
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Nucleic Acid Conformation

Rats

Repetitive Sequences, Nucleic Acid

Sarcoma

Transformation, Genetic

Tumor Cells, Cultured

Source

Open in PubMed

Identifiers

PMID: 2174963
DOI: 10.1099/0022-1317-71-11-2731

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2174963-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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