Article
Oncogenic transformation by BK virus and association with human tumors.
Oncogene - 11 Aug 2003
Tognon Mauro, Corallini Alfredo, Martini Fernanda, Negrini Massimo, Barbanti-Brodano Giuseppe
Abstract excerpt
BK virus (BKV), a human polyomavirus closely related to JC virus and Simian Virus 40, is ubiquitous in human populations worldwide. After primary infection, BKV establishes a lifelong latent infection in many organs. BKV transforms rodent cells to the neoplastic phenotype and is highly oncogenic in rodents. This review considers the oncogenic potential of BKV in humans and its possible involvement in human...
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