Article
GABA(A) receptor- and GABA transporter polymorphisms and risk for essential tremor.
European journal of neurology - 1 Aug 2011
Thier S, Kuhlenbäumer G, Lorenz D, Nothnagel M, Nebel A, Christensen K, Schreiber S, Deuschl G, Klebe S
Abstract excerpt
BACKGROUND: Clinical features and animal models of essential tremor (ET) suggest gamma-aminobutyric acid A receptor (GABA(A) R) subunits and GABA transporters as putative candidate genes. METHODS: A total of 503 ET cases and 818 controls were investigated for an association between polymorphisms in 15 GABA(A) R and four GABA transporter genes and ET. RESULTS: Nine nominally significant tagging SNPs (P values from...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
