Article
The GABA Hypothesis in Essential Tremor: Lights and Shadows
21 May 2014
Abstract excerpt
BACKGROUND: The gamma-aminobutyric acid (GABA) hypothesis in essential tremor (ET) implies a disturbance of the GABAergic system, especially involving the cerebellum. This review examines the evidence of the GABA hypothesis. METHODS: The review is based on published data about GABA dysfunction in ET, taking into account studies on cerebrospinal fluid, pathology, electrophysiology, genetics, neuroimaging,...
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