The functional SNP rs4376531 in the ARHGEF gene is a risk factor for the atherothrombotic stroke in Han Chinese.

doi:10.4103/0028-3886.82755

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Article

The functional SNP rs4376531 in the ARHGEF gene is a risk factor for the atherothrombotic stroke in Han Chinese.

Neurology India - 1 Jan 2000

Yin Yan-Ying, Zhang Bo, Zhou Mu-Ke, Guo Jian, Lei Lei, He Xiang-Hua, Xu Yan-Ming, He Li

Abstract excerpt

The gene encoding RhoA guanine nucleotide exchange factor 10(ARHGEF10) has been reported to be a risk factor for atherothrombotic stroke (AS) in Japanese. The single-nucleotide polymorphism (SNP) rs4376531 in intron 16 on ARHGEF10 is associated with AS and may play a role in the disease pathology. In order to explore the nature of this association in greater detail and in a new ethnic group, we carried out a...

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PMID: 21743172
DOI: 10.4103/0028-3886.82755

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ARHGEF10

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