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Article

Autoantibodies to villin occur frequently in IPEX, a severe immune dysregulation, syndrome caused by mutation of FOXP3.

Clinical immunology (Orlando, Fla.) - 1 Oct 2011

Kobayashi Ichiro, Kubota Mitsuru, Yamada Masafumi, Tanaka Hiroshi, Itoh Shuichi, Sasahara Yoji, Whitesell Luke, Ariga Tadashi

Abstract excerpt

Intractable diarrhea is a major symptom of immune dysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX) syndrome and associated with autoantibodies against enterocytes. Although autoimmune enteropathy (AIE)-related 75 kDa antigen (AIE-75) is a prominent autoantigen involved in the enteropathy associated with IPEX syndrome, some patients with this syndrome demonstrated autoantibody recognizing a 95 kDa...

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Source

Identifiers

PMID: 21741320
DOI: 10.1016/j.clim.2011.05.010

Genes

FOXP3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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