Article
Changes in the somatotrophic axis in genetically identical dogs.
Cellular reprogramming - 1 Oct 2011
Park JungEun, Oh HyunJu, Kim MinJung, Kim GeonA, Park EunJung, Jang Goo, Lee ByeongChun
Abstract excerpt
Because cloned dogs are genetically identical, variations among these animals can be a useful tool to elucidate mechanisms underlying phenotypic differences. To estimate the influence of genetic factors on phenotypic variation, changes in concentration patterns of growth hormone (GH), insulin like growth factor-1 (IGF-1), and IGF binding protein 3 (IGFBP-3) were compared among cloned and age-matched control dogs....
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