Article
Genetic analysis of MA4079, an aldehyde dehydrogenase homolog, in Methanosarcina acetivorans.
Archives of microbiology - 1 Feb 2012
Kliefoth Michael, Langer Julian D, Matschiavelli Nicole, Oelgeschläger Ellen, Rother Michael
Abstract excerpt
When Methanosarcina acetivorans grows on carbon monoxide (CO), it synthesizes high levels of a protein, MA4079, homologous to aldehyde dehydrogenases. To investigate the role of MA4079 in M. acetivorans, mutants lacking the encoding gene were generated and phenotypically analyzed. Loss of MA4079 had no effect on methylotrophic growth but led to complete abrogation of methylotrophic growth...
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