Article
Val/Val genotype of brain-derived neurotrophic factor (BDNF) Val⁶⁶Met polymorphism is associated with a better response to OROS-MPH in Korean ADHD children.
The international journal of neuropsychopharmacology - 1 Nov 2011
Kim Bung-Nyun, Cummins Tarrant D R, Kim Jae-Won, Bellgrove Mark A, Hong Soon-Beom, Song Sook-Hyung, Shin Min-Sup, Cho Soo-Churl, Kim Ji-Hoon, Son Jung-Woo, Shin Yun-Mi, Chung Un-Sun, Han Doug-Hyun
Abstract excerpt
Research on psychostimulants, analysis of animal models and genetic association studies all suggest that the brain-derived neurotrophic factor gene (BDNF) may be a good candidate for pharmacogenetic studies of attention deficit hyperactivity disorder (ADHD). Yet to date there have been no pharmacogenetic studies of BDNF in ADHD. A total of 102 drug-naive ADHD children (8.7±2.1 yr) were treated with osmotic...
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