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Article

Circadian rhythms in Neurospora crassa: lipid deficiencies restore robust rhythmicity to null frequency and white-collar mutants.

Proceedings of the National Academy of Sciences of the United States of America - 4 Jan 2000

Lakin-Thomas P L, Brody S

Abstract excerpt

The conidiation rhythm in the fungus Neurospora crassa is a model system for investigating the genetics of circadian clocks. Null mutants at the frq (frequency) locus (frq(9) and frq(10)) make no functional frq gene products and are arrhythmic under standard conditions. The white-collar strains (wc-1 and wc-2) are insensitive to most effects of light, and are also arrhythmic. All three genes are proposed to be...

Topics

Cell Division
Choline
Circadian Rhythm
Fungal Proteins
Genes, Fungal
Light
Lipids
Mutation
Neurospora crassa
Periodicity
Temperature

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Identifiers

PMID: 10618405
DOI: 10.1073/pnas.97.1.256
PMCID: PMC26650

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