Article
Screening trematodes for novel intervention targets: a proteomic and immunological comparison of Schistosoma haematobium, Schistosoma bovis and Echinostoma caproni.
Parasitology - 1 Oct 2011
Higón Melissa, Cowan Graeme, Nausch Norman, Cavanagh David, Oleaga Ana, Toledo Rafael, Stothard J Russell, Antúnez Oreto, Marcilla Antonio, Burchmore Richard, Mutapi Francisca
Abstract excerpt
With the current paucity of vaccine targets for parasitic diseases, particularly those in childhood, the aim of this study was to compare protein expression and immune cross-reactivity between the trematodes Schistosoma haematobium, S. bovis and Echinostoma caproni in the hope of identifying novel intervention targets. Native adult parasite proteins were separated by 2-dimensional gel electrophoresis and...
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