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Article

Genotype association of C(-735)T polymorphism of the MMP-2 gene with the risk of carotid atherosclerosis-vulnerable plaque in the Han Chinese population.

Vascular medicine (London, England) - 1 Feb 2011

Wang Feng, Jin Xiao-Ping, Zhu Min, Lin Xian-Fang, Hu Xiao-Fei, Wang Wan-Fen, Han Zhao, Huang Ling-Zhi

Abstract excerpt

The aim of the current study was to explore the possible association of the polymorphism of C(-735)T in MMP-2 with the vulnerable plaque risk in ultrasound-confirmed carotid atherosclerosis cases. Serum MMP-2 levels were measured to investigate the relationship between the MMP-2 level and the genetic variability. The MMP-2 polymorphism was detected by PCR-RFLP in the 243 cases with stable plaque and 221 cases...

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PMID: 21471148
DOI: 10.1177/1358863X10394237

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