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Article

Inactivation of mrcA gene derepresses the basal-level expression of L1 and L2 β-lactamases in Stenotrophomonas maltophilia.

The Journal of antimicrobial chemotherapy - 1 Sept 2011

Lin Cheng-Wen, Lin Hsin-Chieh, Huang Yi-Wei, Chung Tung-Ching, Yang Tsuey-Ching

Abstract excerpt

OBJECTIVES: To characterize the relationship between inactivation of the mrcA gene and β-lactamase expression and β-lactams resistance in Stenotrophomonas maltophilia KJ and to investigate the involvement of ampR, ampN-ampG, ampD(I) and creBC in this. METHODS: The mrcA deletion mutant KJΔmrcA was constructed to investigate the role of this putative penicillin-binding protein 1a (PBP1a) in β-lactamase expression...

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PMID: 21719470
DOI: 10.1093/jac/dkr276

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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